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KAT2B Antibody

KAT2B Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameKAT2B Primary Polyclonal Antibody
Also known asKAT2B PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenKAT2B
SpecificityThis is a highly specific antibody against KAT2B
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range460-510/832
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KAT2B
Gene ID number5591
Swiss ProtP78527
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Ability to phosphorylate p53/TP53 in the presence of supercoiled DNA is dependent on C1D, Also involved in modulation of transcription, Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA, Contributes to the determination of the circadian period length by antagonizing phosphorylation of CRY1 'Ser-588' and increasing CRY1 protein stability, DHX9, Found at the ends of chromosomes, HSPCA, Interacts with CRY1 and CRY2, Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination, MYC and RFA2, May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage, Must be bound to DNA to express its catalytic properties, PARP1, POU2F1, Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, Phosphorylates DCLRE1C, Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C), Recognizes the substrate consensus sequence [ST]-Q, Required to protect and align broken ends of DNA, SRF, The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step, WRN, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, c-Abl/ABL1, c-jun/JUN, histone H1, most likely through an indirect machanism, negatively regulates CRY1 phosphorylation, p53/TP53, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion, thereby regulating DNA damage response mechanism, Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DNA-PK catalytic subunit, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, DNAPK, DNPK1, HYRC1, IMD26, PRKDC, XRCC7, p350, p460, HYRC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetKAT2B
Short nameKAT2B Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKAT2B (Antibody to)
Alternative techniqueantibodies
Identity 8638
Gene KAT2B
Long gene name lysine acetyltransferase 2B
Synonyms gene PCAF
Synonyms gene name p300/CBP-associated factor K(lysine) acetyltransferase 2B
Synonyms P/CAF GCN5 GCN5L
Locus 3p24, 3
Discovery year 1999-02-10
GenBank acession U57316
Entrez gene record 8850
Pubmed identfication 8684459 9722949
RefSeq identity NM_003884
Classification Lysine acetyltransferases GCN5 related N-acetyltransferases ATAC complex SAGA complex
Havana BLAST/BLAT OTTHUMG00000130481

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