Name : KCNA5 Antibody / Kv1.5
Supplier : NJS POLY
Price :406
SKU : GEN8470343373
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | 5, KCNA5 / Kv1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 1-0, 5ug/ml, Western blot: 0 |
| Notes | Optimal dilution of the KCNA5 antibody should be determined by the researcher |
| Intented use | This KCNA5 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P22460 |
| Purity | Antigen affinity |
| Description | It belongs to the delayed rectifier class, KCNA5 are also key players in pulmonary vascular function, KCNA5 encodes a member of the potassium channel, Mutations in this gene have been related to both atrial fibrillation and sudden cardiac death, Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints, This gene is intronless, This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment, also known as KCNA5 or Kv1, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12, is a protein that in humans is encoded by the KCNA5 gene, member 5, shaker-related subfamily, shaker-related subfamily, the function of which could restore the resting membrane potential of beta cells after depolarization, thereby contributing to the regulation of insulin secretion, voltage-gated, where they play a role in setting the resting membrane potential and its involvement during hypoxic pulmonary vasoconstriction, 5, Potassium voltage-gated channel |
| Immunogen | Amino acids LEKCNVKAKSNVDLRRSLYALCLDTSRETDL of human KCNA5 were used as the immunogen for the KCNA5 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the KCNA5 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | 5, KCNA5 / Kv1 |
| Short name | 5, KCNA5 Antibody / Kv1 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 5, KCNA5 (Antibody to) / Kv1 |
| Alternative technique | antibodies |
| Identity | 6224 |
| Gene | KCNA5 |
| Long gene name | potassium voltage-gated channel subfamily A member 5 |
| Synonyms gene name | member 5 , potassium voltage-gated channel, shaker-related subfamily |
| Synonyms | Kv1, 5 HK2 HPCN1 |
| Locus | 12p13, 32 |
| Discovery year | 1991-08-13 |
| GenBank acession | M83254 |
| Entrez gene record | 3741 |
| Pubmed identfication | 16382104 |
| RefSeq identity | NM_002234 |
| Classification | Potassium voltage-gated channels |
| Havana BLAST/BLAT | OTTHUMG00000168232 |