Name : KCNMB1 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3264103744
| Long name | ALEXA FLUOR 594 Conjugated, KCNMB1 Polyclonal Antibody |
| Also known as | Anti-KCNMB1 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | KCNMB1 |
| Specificity | This is a highly specific antibody against KCNMB1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCNMB1 |
| Gene ID Number | 3779 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1, Increases the apparent Ca2+/voltage sensitivity of the KCNMA1 channel, Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate, It also modifies KCNMA1 channel kinetics and alters its pharmacological properties, It slows down the activation and the deactivation kinetics of the channel, Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2), Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity, Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | hslo-beta |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | KCNMB1 |
| Short name | KCNMB1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, KCNMB1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6285 |
| Gene | KCNMB1 |
| Long gene name | potassium calcium-activated channel subfamily M regulatory beta subunit 1 |
| Synonyms gene name | beta member 1 potassium channel subfamily M regulatory beta subunit 1 , potassium large conductance calcium-activated channel, subfamily M |
| Synonyms name | BK channel beta subunit 1 MaxiK channel beta-subunit 1 big potassium channel beta subunit 1 |
| Locus | 5q35, 1 |
| Discovery year | 1997-12-05 |
| GenBank acession | AF035046 |
| Entrez gene record | 3779 |
| Pubmed identfication | 8799178 9888999 |
| Classification | Potassium calcium-activated channel subfamily M regulatory beta subunits |
| Havana BLAST/BLAT | OTTHUMG00000130439 |