Name : KCNQ1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3957785258
| Long name | KCNQ1 Primary Polyclonal Antibody |
| Also known as | KCNQ1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | KCNQ1 |
| Specificity | This is a highly specific antibody against KCNQ1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 500-550/676 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCNQ-1 |
| Gene ID number | 3784 |
| Swiss Prot | P51787 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Dog, Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current, Elicits a rapidly activating, May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors, potassium-selective outward current, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea, Probably important in cardiac repolarization |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ATFB1, ATFB3, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, JLNS1, KCNA8, KCNA9, KCNQ1, KQT-like 1, KVLQT1, Kv1, Kv7, LQT1, Potassium voltage-gated channel subfamily KQT member 1, RWS, SQT2, Voltage-gated potassium channel subunit Kv7, WRS, 1, 1, 9, LQT |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | KCNQ1 |
| Short name | KCNQ1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | KCNQ1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6294 |
| Gene | KCNQ1 |
| Long gene name | potassium voltage-gated channel subfamily Q member 1 |
| Synonyms gene | LQT KCNA9 |
| Synonyms gene name | KQT-like subfamily, member 1 , member 1 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q |
| Synonyms | Kv7, 1 KCNA8 KVLQT1 JLNS1 LQT1 |
| Synonyms name | Jervell and Lange-Nielsen syndrome 1 |
| Locus | 11p15, 4 , 5-p15 |
| Discovery year | 1997-02-05 |
| GenBank acession | AF000571 |
| Entrez gene record | 3784 |
| Pubmed identfication | 8528244 16382104 |
| RefSeq identity | NM_000218 |
| Classification | Potassium voltage-gated channels |
| Havana BLAST/BLAT | OTTHUMG00000009900 |
| Locus Specific Databases | Gene Connection for the Heart KCNQ1 database at LOVD-China CCHMC-BMI &, UC Hearing Loss Mutation Database LRG_287 |