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KCNQ1 Antibody

KCNQ1 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameKCNQ1 Primary Polyclonal Antibody
Also known asKCNQ1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenKCNQ1
SpecificityThis is a highly specific antibody against KCNQ1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range500-550/676
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCNQ-1
Gene ID number3784
Swiss ProtP51787
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Dog, Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current, Elicits a rapidly activating, May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors, potassium-selective outward current, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea, Probably important in cardiac repolarization
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ATFB1, ATFB3, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, JLNS1, KCNA8, KCNA9, KCNQ1, KQT-like 1, KVLQT1, Kv1, Kv7, LQT1, Potassium voltage-gated channel subfamily KQT member 1, RWS, SQT2, Voltage-gated potassium channel subunit Kv7, WRS, 1, 1, 9, LQT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetKCNQ1
Short nameKCNQ1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKCNQ1 (Antibody to)
Alternative techniqueantibodies
Identity 6294
Gene KCNQ1
Long gene name potassium voltage-gated channel subfamily Q member 1
Synonyms gene LQT KCNA9
Synonyms gene name KQT-like subfamily, member 1 , member 1 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q
Synonyms Kv7, 1 KCNA8 KVLQT1 JLNS1 LQT1
Synonyms name Jervell and Lange-Nielsen syndrome 1
Locus 11p15, 4 , 5-p15
Discovery year 1997-02-05
GenBank acession AF000571
Entrez gene record 3784
Pubmed identfication 8528244 16382104
RefSeq identity NM_000218
Classification Potassium voltage-gated channels
Havana BLAST/BLAT OTTHUMG00000009900
Locus Specific Databases Gene Connection for the Heart KCNQ1 database at LOVD-China CCHMC-BMI &, UC Hearing Loss Mutation Database LRG_287

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