Name : KCNQ1 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7658004962
| Long name | ALEXA FLUOR 488 Conjugated, KCNQ1 Polyclonal Antibody |
| Also known as | Anti-KCNQ1 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | KCNQ1 |
| Specificity | This is a highly specific antibody against KCNQ1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 500-550/676 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCNQ-1 |
| Gene ID Number | 3784 |
| Swiss Prot | P51787 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Dog, Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current, Elicits a rapidly activating, May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors, potassium-selective outward current, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea, Probably important in cardiac repolarization |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | Kv7, 1 KCNA8 KVLQT1 JLNS1 LQT1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the KCNQ1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | KCNQ1 |
| Short name | KCNQ1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, KCNQ1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6294 |
| Gene | KCNQ1 |
| Long gene name | potassium voltage-gated channel subfamily Q member 1 |
| Synonyms gene | LQT KCNA9 |
| Synonyms gene name | KQT-like subfamily, member 1 , member 1 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q |
| Synonyms name | Jervell and Lange-Nielsen syndrome 1 |
| Locus | 11p15, 4 , 5-p15 |
| Discovery year | 1997-02-05 |
| GenBank acession | AF000571 |
| Entrez gene record | 3784 |
| Pubmed identfication | 8528244 16382104 |
| RefSeq identity | NM_000218 |
| Classification | Potassium voltage-gated channels |
| Havana BLAST/BLAT | OTTHUMG00000009900 |
| Locus Specific Databases | Gene Connection for the Heart KCNQ1 database at LOVD-China CCHMC-BMI &, UC Hearing Loss Mutation Database LRG_287 |