Name : KCNQ1 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN1803125713
| Long name | Cy3 Conjugated, KCNQ1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | KCNQ1 |
| Specificity | This is a highly specific antibody against KCNQ1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 500-550/676 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human KCNQ-1 |
| Gene ID number | 3784 |
| Swiss Prot | P51787 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Dog, Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current, Elicits a rapidly activating, May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors, potassium-selective outward current, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea, Probably important in cardiac repolarization |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | Kv7, 1 KCNA8 KVLQT1 JLNS1 LQT1 |
| Properties | 1 of the KCNQ1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | KCNQ1 Conjugated |
| Short name | Conjugated, KCNQ1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, KCNQ1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6294 |
| Gene | KCNQ1 |
| Long gene name | potassium voltage-gated channel subfamily Q member 1 |
| Synonyms gene | LQT KCNA9 |
| Synonyms gene name | KQT-like subfamily, member 1 , member 1 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q |
| Synonyms name | Jervell and Lange-Nielsen syndrome 1 |
| Locus | 11p15, 4 , 5-p15 |
| Discovery year | 1997-02-05 |
| GenBank acession | AF000571 |
| Entrez gene record | 3784 |
| Pubmed identfication | 8528244 16382104 |
| RefSeq identity | NM_000218 |
| Classification | Potassium voltage-gated channels |
| Havana BLAST/BLAT | OTTHUMG00000009900 |
| Locus Specific Databases | Gene Connection for the Heart KCNQ1 database at LOVD-China CCHMC-BMI &, UC Hearing Loss Mutation Database LRG_287 |