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KCNQ1 Antibody, FITC Conjugated

KCNQ1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, KCNQ1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenKCNQ1
SpecificityThis is a highly specific antibody against KCNQ1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range500-550/676
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human KCNQ-1
Gene ID number3784
Swiss ProtP51787
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Dog, Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current, Elicits a rapidly activating, May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors, potassium-selective outward current, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea, Probably important in cardiac repolarization
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms Kv7, 1 KCNA8 KVLQT1 JLNS1 LQT1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetKCNQ1 Conjugated
Short name FITC Conjugated, KCNQ1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, KCNQ1 (Antibody to)
Alternative techniqueantibodies
Identity 6294
Gene KCNQ1
Long gene name potassium voltage-gated channel subfamily Q member 1
Synonyms gene LQT KCNA9
Synonyms gene name KQT-like subfamily, member 1 , member 1 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q
Synonyms name Jervell and Lange-Nielsen syndrome 1
Locus 11p15, 4 , 5-p15
Discovery year 1997-02-05
GenBank acession AF000571
Entrez gene record 3784
Pubmed identfication 8528244 16382104
RefSeq identity NM_000218
Classification Potassium voltage-gated channels
Havana BLAST/BLAT OTTHUMG00000009900
Locus Specific Databases Gene Connection for the Heart KCNQ1 database at LOVD-China CCHMC-BMI &, UC Hearing Loss Mutation Database LRG_287

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