Name : KCNQ2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4601436650
| Long name | KCNQ2 Primary Polyclonal Antibody |
| Also known as | KCNQ2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | KCNQ2 |
| Specificity | This is a highly specific antibody against KCNQ2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCNQ2 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Benign familial neonatal convulsions (BFNC), Both proteins display a broad distribution within the brain, Epilepsy results from an electrical hyperexcitability in the central nervous system, KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains, Potassium channels are important regulators of electrical signaling, an autosomal dominant epilepsy of infancy, determining the firing properties and responsiveness of a variety of neurons, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes, with expression patterns that largely overlap, &euro, &trade, 5% of the worldâ, Epilepsy affects about 0, s population and has a large genetic component |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BFNS1, EBN, EBN 1, EBN1, EIEE7, ENB 1, ENB1, HNSPC, KCNA 11, KCNA11, KCNQ 2, KCNQ2_HUMAN, KQT like 2, KQT-like 2, KV7, KVEBN 1, KVEBN1, Kcnq2, KvLQT 2, KvLQT2, Neuroblastoma specic potassium channel alpha subunit KvLQT2, Neuroblastoma specic potassium channel protein, Neuroblastoma specic potassium channel subunit alpha, Neuroblastoma specic potassium channel subunit alpha KvLQT2, Neuroblastoma-specic potassium channel subunit alpha KvLQT2, Potassium voltage gated channel KQT like protein 2, Potassium voltage gated channel KQT like subfamily member 2, Potassium voltage gated channel subfamily KQT member 2, Potassium voltage-gated channel subfamily KQT member 2, Voltage gated potassium channel subunit Kv7, Voltage-gated potassium channel subunit Kv7, 2, 2, 2, BFNC |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | KCNQ2 |
| Short name | KCNQ2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | KCNQ2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6296 |
| Gene | KCNQ2 |
| Long gene name | potassium voltage-gated channel subfamily Q member 2 |
| Synonyms gene | EBN EBN1 |
| Synonyms gene name | KQT-like subfamily, member 2 , member 2 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q |
| Synonyms | Kv7, 2 ENB1 BFNC KCNA11 HNSPC |
| Locus | 20q13, 33 |
| Discovery year | 1998-01-12 |
| GenBank acession | AF033348 |
| Entrez gene record | 3785 |
| Pubmed identfication | 9425895 16382104 |
| RefSeq identity | NM_172109 |
| Classification | Potassium voltage-gated channels |
| Havana BLAST/BLAT | OTTHUMG00000033049 |