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KCNQ2 Antibody, Biotin Conjugated

KCNQ2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, KCNQ2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenKCNQ2
SpecificityThis is a highly specific antibody against KCNQ2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human KCNQ2
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Benign familial neonatal convulsions (BFNC), Both proteins display a broad distribution within the brain, Epilepsy results from an electrical hyperexcitability in the central nervous system, KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains, Potassium channels are important regulators of electrical signaling, an autosomal dominant epilepsy of infancy, determining the firing properties and responsiveness of a variety of neurons, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes, with expression patterns that largely overlap, &euro, &trade, 5% of the worldâ, Epilepsy affects about 0, s population and has a large genetic component
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Kv7, 2 ENB1 BFNC KCNA11 HNSPC
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetKCNQ2 Conjugated
Short name Conjugated, KCNQ2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, KCNQ2 (Antibody to)
Alternative techniqueantibodies
Identity 6296
Gene KCNQ2
Long gene name potassium voltage-gated channel subfamily Q member 2
Synonyms gene EBN EBN1
Synonyms gene name KQT-like subfamily, member 2 , member 2 potassium channel, potassium voltage-gated channel, voltage gated KQT-like subfamily Q
Locus 20q13, 33
Discovery year 1998-01-12
GenBank acession AF033348
Entrez gene record 3785
Pubmed identfication 9425895 16382104
RefSeq identity NM_172109
Classification Potassium voltage-gated channels
Havana BLAST/BLAT OTTHUMG00000033049

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