Name : KCNT2 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8618838745
| Long name | Biotin Conjugated, KCNT2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | KCNT2 |
| Specificity | This is a highly specific antibody against KCNT2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human KCNT2 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Its channel activity is inhibited by ATP, KCNT2 is a 1, KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels, There are four isoforms of KCNT2 that are produced as a result of alternative splicing events, and upon stimulation of G-protein coupled receptors, controlling the repolarization and the frequency of action potentials in neurons, inhalation anesthetics, muscles and other excitable cells, such as isoflourane, such as mAChR M1 and GluR-1, 135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins, Voltage-gated K+ channels in the plasma membrane are important regulators of electrical signaling |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | KCa4, 1 , 2 SLICK SLO2 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | KCNT2 Conjugated |
| Short name | Conjugated, KCNT2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, KCNT2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 18866 |
| Gene | KCNT2 |
| Long gene name | potassium sodium-activated channel subfamily T member 2 |
| Synonyms gene name | member 2 , member 2 potassium channel, potassium channel, sodium activated subfamily T, subfamily T |
| Synonyms name | sodium and chloride activated ATP sensitive potassium channel |
| Locus | 1q31, 3 |
| Discovery year | 2002-07-10 |
| GenBank acession | BX647852 AY359444 AK127807 |
| Entrez gene record | 343450 |
| Pubmed identfication | 16382103 |
| RefSeq identity | NM_198503 |
| Classification | Potassium sodium-activated channel subfamily T |
| Havana BLAST/BLAT | OTTHUMG00000035611 |