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KCTD11 Antibody

KCTD11 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameKCTD11 Primary Polyclonal Antibody
Also known asKCTD11 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenKCTD11
SpecificityThis is a highly specific antibody against KCTD11
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KCTD11
Gene ID number147040
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1, Induces apoptosis, Its inactivation might lead to a deregulation of the tumor promoting Hedgehog pathway in medulloblastoma, Plays a role as a marker and a regulator of neuronal differentiation, Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB), Up-regulated by a variety of neurogenic signals, epidermal growth factor/EGF and NGFB/nerve growth factor, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B, such as retinoic acid, thus maintaining cerebellar granule cells in undifferentiated state, The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C 17 orf 36, KCD11_HUMAN, MGC 129844, Potassium channel tetramerisation domain containing 11, REN, Retinoic acid EGF NGF induced gene protein, C17orf36
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetKCTD11
Short nameKCTD11 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKCTD11 (Antibody to)
Alternative techniqueantibodies
Identity 21302
Gene KCTD11
Long gene name potassium channel tetramerization domain containing 11
Synonyms gene C17orf36
Synonyms gene name chromosome 17 open reading frame 36 potassium channel tetramerisation domain containing 11
Synonyms REN KCASH1
Locus 17p13, 1
Discovery year 2003-06-10
GenBank acession AK056227
Entrez gene record 147040
Pubmed identfication 12186855 21472142
RefSeq identity NM_001002914
Havana BLAST/BLAT OTTHUMG00000132061

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