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KDM5A Antibody , Cy7 Conjugated

KDM5A Antibody , Cy7 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy7 Conjugated, KDM5A Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenKDM5A
SpecificityThis is a highly specific antibody against KDM5A
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range130-160/1690
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human KDM5A
Gene ID number5927
Swiss ProtP29375
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4', Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20', In a histone demethylase-independent manner, May be involved in transcriptional regulation of Hox proteins during cell differentiation, May participate in transcriptional repression of cytokines such as CXCL12, May stimulate transcription mediated by nuclear receptors, Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 (By similarity), thereby playing a central role in histone code, Histone demethylase that specifically demethylates 'Lys-4' of histone H3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetKDM5A Conjugated
Short nameKDM5A Antibody Conjugated
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, KDM5A (Antibody to)
Alternative techniqueantibodies
Identity 9886
Gene KDM5A
Long gene name lysine demethylase 5A
Synonyms gene RBBP2 JARID1A
Synonyms gene name AT rich interactive domain 1A (RBBP2-like) jumonji, AT rich interactive domain 1A lysine (K)-specific demethylase 5A , retinoblastoma-binding protein 2 Jumonji
Locus 12p13, 33
Discovery year 1992-09-17
Entrez gene record 5927
Pubmed identfication 1857421
RefSeq identity NM_005056
Classification PHD finger proteins Lysine demethylases AT-rich interaction domain containing EMSY complex
Havana BLAST/BLAT OTTHUMG00000168055

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