Name : KDM5A Antibody , Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN2942836135
| Long name | Cy7 Conjugated, KDM5A Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | KDM5A |
| Specificity | This is a highly specific antibody against KDM5A |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 130-160/1690 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human KDM5A |
| Gene ID number | 5927 |
| Swiss Prot | P29375 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4', Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20', In a histone demethylase-independent manner, May be involved in transcriptional regulation of Hox proteins during cell differentiation, May participate in transcriptional repression of cytokines such as CXCL12, May stimulate transcription mediated by nuclear receptors, Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 (By similarity), thereby playing a central role in histone code, Histone demethylase that specifically demethylates 'Lys-4' of histone H3 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | KDM5A Conjugated |
| Short name | KDM5A Antibody Conjugated |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, KDM5A (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9886 |
| Gene | KDM5A |
| Long gene name | lysine demethylase 5A |
| Synonyms gene | RBBP2 JARID1A |
| Synonyms gene name | AT rich interactive domain 1A (RBBP2-like) jumonji, AT rich interactive domain 1A lysine (K)-specific demethylase 5A , retinoblastoma-binding protein 2 Jumonji |
| Locus | 12p13, 33 |
| Discovery year | 1992-09-17 |
| Entrez gene record | 5927 |
| Pubmed identfication | 1857421 |
| RefSeq identity | NM_005056 |
| Classification | PHD finger proteins Lysine demethylases AT-rich interaction domain containing EMSY complex |
| Havana BLAST/BLAT | OTTHUMG00000168055 |