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KDM5B Antibody

KDM5B Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameKDM5B Primary Polyclonal Antibody
Also known asKDM5B PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenKDM5B
SpecificityThis is a highly specific antibody against KDM5B
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range80-130/1544
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KDM5B/Jarid1B
Gene ID number10765
Swiss ProtQ9UGL1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a transcriptional corepressor for FOXG1B and PAX9, Demethylates trimethylated, Does not demethylate histone H3 'Lys-9' or H3 'Lys-27', Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5, In contrast, Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity), dimethylated and monomethylated H3 'Lys-4', may act as a tumor suppressor for melanoma, thereby playing a central role in histone code, Histone demethylase that demethylates 'Lys-4' of histone H3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cancer/testis antigen 31, Histone demethylase JARID1B, JARID1B, Jumonji/ARID domain-containing protein 1B, KDM5B, Lysine-specific demethylase 5B, PLU-1, PLU1, PPP1R98, PUT1, RBBP2H1, RBBP2H1A, RBP2-H1, Retinoblastoma-binding protein 2 homolog 1, CT31
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetKDM5B
Short nameKDM5B Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKDM5B (Antibody to)
Alternative techniqueantibodies
Identity 18039
Gene KDM5B
Long gene name lysine demethylase 5B
Synonyms gene JARID1B
Synonyms gene name AT rich interactive domain 1B (RBP2-like) jumonji, AT rich interactive domain 1B lysine (K)-specific demethylase 5B , Jumonji
Synonyms RBBP2H1A PLU-1 CT31 PPP1R98
Synonyms name cancer/testis antigen 31 protein phosphatase 1, regulatory subunit 98
Locus 1q32, 1
Discovery year 2004-01-28
GenBank acession AJ243706
Entrez gene record 10765
Pubmed identfication 11483573 11478881
RefSeq identity NM_006618
Classification PHD finger proteins Lysine demethylases AT-rich interaction domain containing
Havana BLAST/BLAT OTTHUMG00000041401

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