Name : KDM5B Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3669503016
| Long name | ALEXA FLUOR 647 Conjugated, KDM5B Polyclonal Antibody |
| Also known as | Anti-KDM5B PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | KDM5B |
| Specificity | This is a highly specific antibody against KDM5B |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 80-130/1544 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KDM5B/Jarid1B |
| Gene ID Number | 10765 |
| Swiss Prot | Q9UGL1 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Acts as a transcriptional corepressor for FOXG1B and PAX9, Demethylates trimethylated, Does not demethylate histone H3 'Lys-9' or H3 'Lys-27', Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5, In contrast, Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity), dimethylated and monomethylated H3 'Lys-4', may act as a tumor suppressor for melanoma, thereby playing a central role in histone code, Histone demethylase that demethylates 'Lys-4' of histone H3 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | RBBP2H1A PLU-1 CT31 PPP1R98 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the KDM5B Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | KDM5B |
| Short name | KDM5B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, KDM5B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 18039 |
| Gene | KDM5B |
| Long gene name | lysine demethylase 5B |
| Synonyms gene | JARID1B |
| Synonyms gene name | AT rich interactive domain 1B (RBP2-like) jumonji, AT rich interactive domain 1B lysine (K)-specific demethylase 5B , Jumonji |
| Synonyms name | cancer/testis antigen 31 protein phosphatase 1, regulatory subunit 98 |
| Locus | 1q32, 1 |
| Discovery year | 2004-01-28 |
| GenBank acession | AJ243706 |
| Entrez gene record | 10765 |
| Pubmed identfication | 11483573 11478881 |
| RefSeq identity | NM_006618 |
| Classification | PHD finger proteins Lysine demethylases AT-rich interaction domain containing |
| Havana BLAST/BLAT | OTTHUMG00000041401 |