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KDM5B Antibody, Biotin Conjugated

KDM5B Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, KDM5B Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenKDM5B
SpecificityThis is a highly specific antibody against KDM5B
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range80-130/1544
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human KDM5B/Jarid1B
Gene ID number10765
Swiss ProtQ9UGL1
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a transcriptional corepressor for FOXG1B and PAX9, Demethylates trimethylated, Does not demethylate histone H3 'Lys-9' or H3 'Lys-27', Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5, In contrast, Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity), dimethylated and monomethylated H3 'Lys-4', may act as a tumor suppressor for melanoma, thereby playing a central role in histone code, Histone demethylase that demethylates 'Lys-4' of histone H3
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms RBBP2H1A PLU-1 CT31 PPP1R98
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetKDM5B Conjugated
Short name Conjugated, KDM5B Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, KDM5B (Antibody to)
Alternative techniqueantibodies
Identity 18039
Gene KDM5B
Long gene name lysine demethylase 5B
Synonyms gene JARID1B
Synonyms gene name AT rich interactive domain 1B (RBP2-like) jumonji, AT rich interactive domain 1B lysine (K)-specific demethylase 5B , Jumonji
Synonyms name cancer/testis antigen 31 protein phosphatase 1, regulatory subunit 98
Locus 1q32, 1
Discovery year 2004-01-28
GenBank acession AJ243706
Entrez gene record 10765
Pubmed identfication 11483573 11478881
RefSeq identity NM_006618
Classification PHD finger proteins Lysine demethylases AT-rich interaction domain containing
Havana BLAST/BLAT OTTHUMG00000041401

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