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Keratocan Antibody

Keratocan Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameKeratocan Primary Polyclonal Antibody
Also known asKeratocan PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenKeratocan
SpecificityThis is a highly specific antibody against Keratocan
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Keratocan
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Biglycan, Defects in the gene encoding for Keratocan can cause cornea plana 2 (CNA2), Fibromod-ulin, Fibromodulin is a collagen-binding keratan sulphate proteoglycan that influences adhesion processes of connective tissue and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness, Keratocan, Keratocan (KTN) develops corneal transparency and maintains the stromal matrix structure, Keratocan is a secreted protein in the extracellular matrix that binds to keratan sulfate chains, Keratocan is mainly detected in the cornea, Lumican and Osteoglycin mediate extracellular matrix organization and are binding partners of TGF Beta, The Decorin core protein binds to growth factors, an autosomal recessive disorder where the forward convex curvature of the cornea is flattened, and to the Decorin endocytosis receptor, but can also be expressed in trachea, intercellular matrix molecules such as Fibronectin and Throm-bospondin, intestine, lung and skeletal muscle, ovary, Small leucine-rich proteoglycans (SLRPs) such as Decorin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names KERA, KERA_HUMAN, KTN, Keratan sulfate proteoglycan keratocan, Keratocan, SLRR2B, CNA2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetKeratocan
Short nameKeratocan Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKeratocan (Antibody to)
Alternative techniqueantibodies
Identity 6309
Gene KERA
Long gene name keratocan
Synonyms gene CNA2
Synonyms SLRR2B
Synonyms name keratocan proteoglycan
Locus 12q21, 33
Discovery year 1999-08-26
GenBank acession AF063301
Entrez gene record 11081
Pubmed identfication 10565548 10802664
RefSeq identity NM_007035
Classification Small leucine rich repeat proteoglycans
Havana BLAST/BLAT OTTHUMG00000170073
Locus Specific Databases LRG_538

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