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KiSS1 receptor Antibody

KiSS1 receptor Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameKiSS1 receptor Primary Polyclonal Antibody
Also known asKiSS1 receptor PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenKiSS1 receptor
SpecificityThis is a highly specific antibody against KiSS1 receptor
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range139-157/398
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KiSS1 receptor
Gene ID number84634
Swiss ProtQ969F8
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins, KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity, The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood, The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells, The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself, The receptor is essential for normal gonadotropin-released hormone physiology and for puberty, a C-terminally amidated peptide of KiSS1, Receptor for metastin (kisspeptin-54 or kp-54)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AXOR12, CPPB1, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, GPR54, HOT7T175, Hypogonadotropin-1, KISS-1R, KISS1R, KiSS-1 receptor, Kisspeptins receptor, Metastin receptor, HH8
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetKiSS1 receptor
Short nameKiSS1 receptor Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKiSS1 receptor (Antibody to)
Alternative techniqueantibodies
Identity 4510
Gene KISS1R
Long gene name KISS1 receptor
Synonyms gene GPR54
Synonyms gene name G protein-coupled receptor 54
Synonyms HOT7T175 AXOR12
Locus 19p13, 3
Discovery year 1999-03-12
GenBank acession AB051065
Entrez gene record 84634
Pubmed identfication 10100623
RefSeq identity NM_032551
Classification Peptide receptors
Havana BLAST/BLAT OTTHUMG00000181900

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