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KLF2/4 Antibody

KLF2/4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameKLF2/4 Primary Polyclonal Antibody
Also known asKLF2/4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenKLF2/4
Specificity This antibody may crossreact with KLF2 due to high sequence similarity, This is a highly specific antibody against KLF2/4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range420-470/513
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLF4
Gene ID number9314
Swiss ProtO43474
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds the 5'-CACCC-3' core sequence, Binds to the promoter region of its own gene and can activate its own transcription, Contributes to the down-regulation of p53/TP53 transcription, Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development, Plays an important role in maintaining embryonic stem cells, Regulates the expression of key transcription factors during embryonic development, Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface, and in preventing their differentiation, can act both as activator and as repressor, Transcription factor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Epithelial zinc finger protein EZF, GKLF, Gut-enriched krueppel-like factor, KLF4, Krueppel-like factor 4, EZF
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetKLF2/4
Short nameKLF2/4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKruppel-like factor 2 (lung)/4 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0034101 and erythrocyte homeostasis and biological process this GO :0034616 and response to laminar fluid shear stress and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0036003 and positive regulation of transcription from RNA polymerase II promoter in response to stress and biological process this GO :0040029 and regulation of gene expression, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0051247 and positive regulation of protein metabolic process and biological process this GO :0060509 and Type I pneumocyte differentiation and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071409 and cellular response to cycloheximide and biological process this GO :0071499 and cellular response to laminar fluid shear stress and biological process this GO :1901653 and cellular response to peptide and biological process, KLF2 and IDBG-35485 and ENSG00000127528 and 10365, Klf2 and IDBG-167841 and ENSMUSG00000055148 and 16598, LKLF, epigenetic and biological process this GO :0043249 and erythrocyte maturation and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045893 and positive regulation of transcription, metal ion binding, nuclei, this GO :0000902 and cell morphogenesis and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0046872: metal ion binding, this GO :0005515: protein binding, this GO :0043565: sequence-specific DNA binding, this GO :0046872: metal ion binding, Kruppel-like factor 2 (lung)
Identity 6347
Gene KLF2
Long gene name Kruppel like factor 2
Synonyms gene name Kruppel-like factor 2 (lung)
Synonyms LKLF
Synonyms name lung Kruppel-like factor
Locus 19p13, 11
Discovery year 1999-12-14
GenBank acession AF123344
Entrez gene record 10365
Pubmed identfication 10217429 10458913
Classification Kruppel like factors Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000182330

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