KLF8 Antibody

KLF8 Antibody size: 0.1mg 389

Price 389

Size 0.1mg

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Category	Antibody
Concentration	2ml sterile DI water, 5mg/ml if reconstituted with 0
Form	Antigen affinity purified
Conjugation	Unconjugated
Clone	Polyclonal antibody
Recognised antigen	KLF8
Host animal	Rabbit (Oryctolagus cuniculus)
Clonality	Polyclonal (rabbit origin)
Species reactivity	Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications	WB
Recommended dilutions	5-1ug/ml, Western blot: 0
Notes	Titration of the KLF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented use	This KLF8 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #	O95600
Purity	Antigen affinity
Description	Expression of KLF8 or only its zinc fingers showed that the fingers could bind to a CACCC box, It is also named as ZNF741, Kruppel-like factor proteins all contain a characteristic C-terminal DNA-binding domain containing three Kruppel-like zinc fingers, Sequence analysis predicted that the 359-amino acid protein contains a nuclear localization signal upstream of the zinc fingers, Suske et al, The International Radiation Hybrid Mapping Consortium mapped the gene to the X chromosome (WI-18614), Yeast 2-hybrid and GST pull-down analysis demonstrated that CTBP2 interacts with KLF8 through the PVDLS motif, a valine-rich hydrophobic stretch, also called ZNF741, and a pro-val-asp-leu-ser(PVDLS) motif, and the mouse gene to chromosome XF3, and they all recognize CACCC and GC boxes present in promoters and enhancers, or BKLF3, van Vliet et al, (2000) identified a cDNA encoding KLF8, (2005) stated that the human gene maps to chromosome Xp11, 21, Kruppel-like factor 8 is a protein that in humans is encoded by the KLF8 gene
Immunogen	An amino acid sequence from the N-terminus of human Kruppel-like factor 8 (MVDMDKLINNLEVQLNSE) was used as the immunogen for this KLF8 antibody
Storage	Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the KLF8 antibody can be stored for up to one month at 4oC, After reconstitution
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target	KLF8
Short name	KLF8 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	KLF8 (Antibody to)
Alternative technique	antibodies
Identity	6351
Gene	KLF8
Long gene name	Kruppel like factor 8
Synonyms	BKLF3 ZNF741 DXS741
Locus	Xp11, 21
Discovery year	2000-03-14
GenBank acession	U28282
Entrez gene record	11279
RefSeq identity	NM_007250
Classification	Kruppel like factors Zinc fingers C2H2-type
Havana BLAST/BLAT	OTTHUMG00000021666

KLF8 Antibody

KLF8 Antibody size: 0.1mg 389

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