Name : KLHL25 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3885994066
| Long name | ALEXA FLUOR 488 Conjugated, KLHL25 Polyclonal Antibody |
| Also known as | Anti-KLHL25 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | KLHL25 |
| Specificity | This is a highly specific antibody against KLHL25 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 435-485/589 |
| Subcellular location | Intracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLHL25 |
| Gene ID Number | 64410 |
| Swiss Prot | Q9H0H3 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E, The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low, Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | FLJ12587 ENC2 ENC-2 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the KLHL25 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | KLHL25 |
| Short name | KLHL25 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, KLHL25 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25732 |
| Gene | KLHL25 |
| Long gene name | kelch like family member 25 |
| Synonyms gene name | kelch-like 25 (Drosophila) |
| Synonyms name | ectodermal-neural cortex 2 |
| Locus | 15q25, 3 |
| Discovery year | 2005-11-17 |
| Entrez gene record | 64410 |
| RefSeq identity | NM_022480 |
| Classification | BTB domain containing Kelch like |
| Havana BLAST/BLAT | OTTHUMG00000148672 |