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Ku-70 Antibody, Cy5 Conjugated

Ku-70 Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, Ku-70 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenKu-70
SpecificityThis is a highly specific antibody against Ku-70
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Ku70
Gene ID number2547
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background High levels of auto to p70 and p80 have been found in some patients with systemic lupus erythematosus, It acts as the regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit (PRKDC) for DNA, Ku70 heterodimerises with Ku80 to form the ATP-dependent DNA helicase II, The Ku70/80 heterodimer is also required for osteocalcin gene expression, The complex functions as a single-stranded DNA-dependent ATP-dependent helicase, The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, The heterodimer plays a role in non-homologous end-joining (NHEJ) required for double-strand break repair and V(D)J recombination, [provided by RefSeq], a single stranded helicase that binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner, and V(D)J recombination, transposition, The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms 70 kDa subunit of Ku antigen, 70 kDa subunit of Ku antigen, 70kDa, ATP dependent DNA helicase 2 subunit 1, ATP dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, G22P1, Ku 70, Ku autoantigen, Ku autoantigen 70kDa, Ku autoantigen p70 subunit, Ku p70, Ku70 DNA binding component of DNA-dependent proteinkinase complex thyroid autoantigen 70 kDa, Kup70, Lupus Ku autoantigen protein p70, ML8, TLAA, Thyroid autoantigen, Thyroid autoantigen 70kD Ku antigen, Thyroid lupus autoantigen, Thyroid lupus autoantigen p70, X ray repair complementing defective repair in Chinese hamster cells 6, XRCC 6, XRCC6, Ku70
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetKu-70 Conjugated
Short name Conjugated, Ku-70 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, Ku-70 (Antibody to)
Alternative techniqueantibodies

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