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L-Selectin Antibody (CD62L)

L-Selectin Antibody (CD62L) size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenL-Selectin (CD62L)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC-P, WB
Recommended dilutions1-0, 1-0, 5-1ug/ml, 5ug/ml, 5ug/ml, ELISA : 0, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the CD62L antibody should be determined by the researcher
Intented useThis CD62L antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P14151
PurityAntigen affinity
Description It belongs to the selectin family of proteins, It is cleaved by ADAM17, L-selectin acts as a homing receptor for leukocytes to enter secondary lymphoid tissues via high endothelial venules, Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions, The molecule is composed of multiple domains: one homologous to lectins, also known as L-selectin, and facilitating entry into a secondary lymphoid organ at that point, and two to the consensus repeat units found in C3/C4 binding proteins, is a cell adhesion molecule found on leukocytes, one to epidermal growth factor, slowing leukocyte trafficking through the blood, which recognize sialylated carbohydrate groups, CD62L
ImmunogenAmino acids 39-372 of human CD62L were used as the immunogen for the CD62L antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CD62L antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetL-Selectin (CD62L)
Short nameL-Selectin Antibody (CD62L)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameL-Selectin (Antibody to) (CD62L)
Alternative techniqueantibodies
Identity 10720
Gene SELL
Long gene name selectin L
Synonyms gene LYAM1 LNHR
Synonyms gene name lymphocyte adhesion molecule 1
Synonyms LSEL LAM1 LAM-1 hLHRc Leu-8 Lyam-1 PLNHR CD62L
Locus 1q24, 2
Discovery year 1989-06-07
GenBank acession M25280
Entrez gene record 6402
Pubmed identfication 2664786 1375831
RefSeq identity NM_000655
Classification Sushi domain containing Selectins CD molecules C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000034809

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