Name : L-Selectin Antibody (CD62L)
Supplier : NJS POLY
Price :406
SKU : GEN3580300017
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | L-Selectin (CD62L) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC-P, WB |
| Recommended dilutions | 1-0, 1-0, 5-1ug/ml, 5ug/ml, 5ug/ml, ELISA : 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the CD62L antibody should be determined by the researcher |
| Intented use | This CD62L antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P14151 |
| Purity | Antigen affinity |
| Description | It belongs to the selectin family of proteins, It is cleaved by ADAM17, L-selectin acts as a homing receptor for leukocytes to enter secondary lymphoid tissues via high endothelial venules, Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions, The molecule is composed of multiple domains: one homologous to lectins, also known as L-selectin, and facilitating entry into a secondary lymphoid organ at that point, and two to the consensus repeat units found in C3/C4 binding proteins, is a cell adhesion molecule found on leukocytes, one to epidermal growth factor, slowing leukocyte trafficking through the blood, which recognize sialylated carbohydrate groups, CD62L |
| Immunogen | Amino acids 39-372 of human CD62L were used as the immunogen for the CD62L antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CD62L antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | L-Selectin (CD62L) |
| Short name | L-Selectin Antibody (CD62L) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | L-Selectin (Antibody to) (CD62L) |
| Alternative technique | antibodies |
| Identity | 10720 |
| Gene | SELL |
| Long gene name | selectin L |
| Synonyms gene | LYAM1 LNHR |
| Synonyms gene name | lymphocyte adhesion molecule 1 |
| Synonyms | LSEL LAM1 LAM-1 hLHRc Leu-8 Lyam-1 PLNHR CD62L |
| Locus | 1q24, 2 |
| Discovery year | 1989-06-07 |
| GenBank acession | M25280 |
| Entrez gene record | 6402 |
| Pubmed identfication | 2664786 1375831 |
| RefSeq identity | NM_000655 |
| Classification | Sushi domain containing Selectins CD molecules C-type lectin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000034809 |