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L1CAM Antibody

L1CAM Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenL1CAM
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000 (1)
Notes Cleavage by ADAM10 results in 180 and 40 kDa bands while cleavage by Plasmin results in 140 and 80 kDa bands, <, 1, Titration of the L1CAM antibody may be required due to differences in protocols and secondary/substrate sensitivity, p>
Intented useThis L1CAM antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P32004
PurityAntigen affinity
Description Alternative splicing of a neuron-specific exon is thought to be functionally relevant, Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, The ectodomain, This cell adhesion molecule plays an important role in nervous system development, aphasia, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), including neuronal migration and differentiation, is linked via a single transmembrane sequence to a conserved cytoplasmic domain, retardation, spastic paraplegia and hydrocephalus), L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family
ImmunogenA portion of amino acids 1154-1182 from the human protein was used as the immunogen for this L1CAM antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the L1CAM antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetL1CAM
Short nameL1CAM Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameL1 cellular adhesion molecule (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CAML1 and CD171 and HSAS and HSAS1 and MASA and MIC5 and N-CAM-L1 and N-CAML1 and NCAM-L1 and S10 and SPG1, Cell surfaces, L1CAM and IDBG-632479 and ENSBTAG00000013462 and 516017, L1CAM and IDBG-90096 and ENSG00000198910 and 3897, L1cam and IDBG-154012 and ENSMUSG00000031391 and 16728, protein self-association, this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008219 and cell death and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0022409 and positive regulation of cell-cell adhesion and biological process this GO :0031175 and neuron projection development and biological process this GO :0033631 and cell-cell adhesion mediated by integrin and biological process this GO :0033691 and sialic acid binding and molecular function this GO :0034109 and homotypic cell-cell adhesion and biological process this GO :0042734 and presynaptic membrane and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0043195 and terminal bouton and cellular component this GO :0043621 and protein self-association and molecular function this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050900 and leukocyte migration and biological process, this GO :0005178: integrin binding, this GO :0005178: integrin binding and also this GO :0005515: protein binding and also this GO :0033691: sialic acid binding and also this GO :0042802: identical protein binding and also this GO :0043621: protein self-association, this GO :0005515: protein binding, this GO :0033691: sialic acid binding, this GO :0042802: identical protein binding, this GO :0043621: protein self-association, L1 cell adhesion molecule
Identity 6470
Gene L1CAM
Long gene name L1 cell adhesion molecule
Synonyms gene HSAS1 SPG1 HSAS MASA MIC5 S10
Synonyms gene name antigen identified by monoclonal antibody R1
Synonyms CD171
Locus Xq28
Discovery year 1989-06-30
GenBank acession M74387
Entrez gene record 3897
RefSeq identity NM_024003
Classification I-set domain containing CD molecules Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000024221
Locus Specific Databases Manchester LOVD LOVD - Leiden Open Variation Database LRG_14 , Mental Retardation database NGRL

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