Name : LAG3 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN8544483960
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | LAG3 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC, WB |
| Recommended dilutions | IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the LAG3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This LAG3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P18627 |
| Purity | Antigen affinity |
| Description | Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains |
| Immunogen | A portion of amino acids 103-132 from the human protein was used as the immunogen for this LAG3 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the LAG3 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | LAG3 |
| Short name | LAG3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | lymphocyte-activation gene 3 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CD223, Cell surfaces, LAG3 and IDBG-14994 and ENSG00000089692 and 3902, Lag3 and IDBG-188462 and ENSMUSG00000030124 and 16768, MHC class II protein binding, this GO :0003823 and antigen binding and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0042289 and MHC class II protein binding and molecular function this GO :0045085 and negative regulation of interleukin-2 biosynthetic process and biological process this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0003823: antigen binding, this GO :0003823: antigen binding and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding and also this GO :0042289: MHC class II protein binding, this GO :0004888: transmembrane signaling receptor activity, this GO :0005515: protein binding, this GO :0042289: MHC class II protein binding, 18959 and IDBG-640276 and ENSBTAG00000034295 and 515155, lymphocyte-activation gene 3 |
| Identity | 6476 |
| Gene | LAG3 |
| Long gene name | lymphocyte activating 3 |
| Synonyms gene name | lymphocyte-activation gene 3 |
| Synonyms | CD223 |
| Locus | 12p13, 31 |
| Discovery year | 1991-06-03 |
| Entrez gene record | 3902 |
| RefSeq identity | NM_002286 |
| Classification | CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT | OTTHUMG00000169197 |