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lamin A/C Antibody, ALEXA FLUOR 555

lamin A/C Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, lamin A/C Polyclonal Antibody
Also known asAnti-lamin A/C PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenlamin A/C
SpecificityThis is a highly specific antibody against lamin A/C
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human lamin A/C
Gene ID Number4000
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A-type lamins and B-type lamins, Besides interactions with the nuclear membrane and other intermediate filaments, Eukaryotic chromatin is organised into loops, Lamins, Many biochemical and molecular features of lamins have been studied, Nuclear lamins form a network of filaments at the nucleoplasmic site of the nuclear membrane, One of the functions ascribed to the lamina is the maintenance of the structural integrity of the nucleus, The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, The nuclear lamins comprise a unique subclass of the intermediate filament protein family, They share a molecular domain organisation with the other intermediate filament proteins in that they are fibrous molecules that have an aminoterminal globular head, This organisation is thought to contribute to compaction of the chromatin and regulation of gene expression, Two main subtypes of nuclear lamins can be distinguished, a central rod of a-helices and a carboxyterminal globular domain, as part of the nuclear matrix, but their functions remain still largely undetermined, i, i, i, lamin A, lamin B1 and lamin B2, lamin C and lamin Adel10, lamins interact with the nuclear chromatin, may be involved in these processes since chromatin binding sites have been detected in both A- and B-type lamins, which are attached to the nuclear matrix, while the B-type lamins include two proteins arising from two distinct genes, Nuclear Envelope Marker An important part of the cell nucleus is formed by nuclear lamina, e, e, e
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms HGPS MADA LMNA
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetlamin A/C
Short namelamin A/C Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, lamin A/C (Antibody to)
Alternative techniqueantibodies
Identity 9450
Gene PRO1
Long gene name lamin A/C
Synonyms gene LMN1 CMD1A LGMD1B LMNL1
Synonyms gene name cardiomyopathy, dilated 1A (autosomal dominant) limb girdle muscular dystrophy 1B (autosomal dominant) progeria 1 (Hutchinson-Gilford type) lamin A/C-like 1
Synonyms name mandibuloacral dysplasia type A
Locus 1q22
Discovery year 1992-04-09
GenBank acession BC014507
Entrez gene record 4000
Pubmed identfication 8511676 8838815 12702809
RefSeq identity NM_170707
Classification Lamins
Havana BLAST/BLAT OTTHUMG00000013961
Locus Specific Databases Inherited Peripheral Neuropathies Mutation Database Leiden Muscular Dystrophy Pages UMD Locus Specific Databases Leiden Muscular Dystrophy pages LRG_254

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