Filters

lamin A/C Antibody, Biotin Conjugated

lamin A/C Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, lamin A/C Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenlamin A/C
SpecificityThis is a highly specific antibody against lamin A/C
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human lamin A/C
Gene ID number4000
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A-type lamins and B-type lamins, Besides interactions with the nuclear membrane and other intermediate filaments, Eukaryotic chromatin is organised into loops, Lamins, Many biochemical and molecular features of lamins have been studied, Nuclear lamins form a network of filaments at the nucleoplasmic site of the nuclear membrane, One of the functions ascribed to the lamina is the maintenance of the structural integrity of the nucleus, The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, The nuclear lamins comprise a unique subclass of the intermediate filament protein family, They share a molecular domain organisation with the other intermediate filament proteins in that they are fibrous molecules that have an aminoterminal globular head, This organisation is thought to contribute to compaction of the chromatin and regulation of gene expression, Two main subtypes of nuclear lamins can be distinguished, a central rod of a-helices and a carboxyterminal globular domain, as part of the nuclear matrix, but their functions remain still largely undetermined, i, i, i, lamin A, lamin B1 and lamin B2, lamin C and lamin Adel10, lamins interact with the nuclear chromatin, may be involved in these processes since chromatin binding sites have been detected in both A- and B-type lamins, which are attached to the nuclear matrix, while the B-type lamins include two proteins arising from two distinct genes, Nuclear Envelope Marker An important part of the cell nucleus is formed by nuclear lamina, e, e, e
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms 70 kDa lamin, FPLD, HGPS, IDC, LDP1, LGMD1B, LMN 1, LMN C, LMNA_HUMAN, Lamin A/C, Lamin-A/C, LaminC, PRO1, Prelamin-A/C, Renal carcinoma antigenNY-REN-32, FPL
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetlamin A/C Conjugated
Short name Conjugated, lamin A/C Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, lamin A/C (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter