Name : lamin A/C Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN5710099576
| Long name | Cy3 Conjugated, lamin A/C Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | lamin A/C |
| Specificity | This is a highly specific antibody against lamin A/C |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human lamin A/C |
| Gene ID number | 4000 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A-type lamins and B-type lamins, Besides interactions with the nuclear membrane and other intermediate filaments, Eukaryotic chromatin is organised into loops, Lamins, Many biochemical and molecular features of lamins have been studied, Nuclear lamins form a network of filaments at the nucleoplasmic site of the nuclear membrane, One of the functions ascribed to the lamina is the maintenance of the structural integrity of the nucleus, The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, The nuclear lamins comprise a unique subclass of the intermediate filament protein family, They share a molecular domain organisation with the other intermediate filament proteins in that they are fibrous molecules that have an aminoterminal globular head, This organisation is thought to contribute to compaction of the chromatin and regulation of gene expression, Two main subtypes of nuclear lamins can be distinguished, a central rod of a-helices and a carboxyterminal globular domain, as part of the nuclear matrix, but their functions remain still largely undetermined, i, i, i, lamin A, lamin B1 and lamin B2, lamin C and lamin Adel10, lamins interact with the nuclear chromatin, may be involved in these processes since chromatin binding sites have been detected in both A- and B-type lamins, which are attached to the nuclear matrix, while the B-type lamins include two proteins arising from two distinct genes, Nuclear Envelope Marker An important part of the cell nucleus is formed by nuclear lamina, e, e, e |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | 70 kDa lamin, FPLD, HGPS, IDC, LDP1, LGMD1B, LMN 1, LMN C, LMNA_HUMAN, Lamin A/C, Lamin-A/C, LaminC, PRO1, Prelamin-A/C, Renal carcinoma antigenNY-REN-32, FPL |
| Properties | 1 of the lamin A/C Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | lamin A/C Conjugated |
| Short name | Conjugated, lamin A/C Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, lamin A/C (Antibody to) |
| Alternative technique | antibodies |