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Lamin B2 Antibody

Lamin B2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLamin B2 Primary Polyclonal Antibody
Also known asLamin B2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLamin B2
SpecificityThis is a highly specific antibody against Lamin B2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lamin B2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen B-type lamins undergo a series of modifications, Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations, Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family, Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, This family, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity, structure and substrate specificity from any previously described protease family, such as farnesylation and phosphorylation, termed CED-3/ICE, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin, A unique family of Cysteine proteases has been described that differs in sequence
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names LAMB2, LMN 2, LMN B2, LMN2, LMNB 2, LMNB2, LMNB2_HUMAN, Lamin-B2, MGC2721, Alternative namesLAMB 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLamin B2
Short nameLamin B2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLamin B2 (Antibody to)
Alternative techniqueantibodies
Identity 6638
Gene LMNB2
Long gene name lamin B2
Synonyms gene LMN2
Locus 19p13, 3
Discovery year 1992-04-09
GenBank acession M94362
Entrez gene record 84823
Pubmed identfication 1630457
RefSeq identity NM_032737
Classification Lamins
Havana BLAST/BLAT OTTHUMG00000150626

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