Name : Laminin gamma 1 Antibody
Supplier : NJS POLY
Price :389
SKU : GEN9833241369
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Laminin gamma 1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Titration of the Laminin gamma 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use | This Laminin gamma 1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P11047 |
| Purity | Antigen affinity |
| Description | B1, Different alpha, Each laminin chain is a multidomain protein encoded by a distinct gene, Laminins, Laminins are composed of 3 non identical chains: laminin alpha, Several isoforms of each chain have been described, The biological functions of the different chains and trimer molecules are largely unknown, The gamma 1 chain, The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes, They have been implicated in a wide variety of biological processes including cell adhesion, This gene encodes the gamma chain isoform, a family of extracellular matrix glycoproteins, and B2, and a long arm composed of all 3 chains, are the major noncollagenous constituent of basement membranes, beta and gamma (formerly A, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, but some have been shown to differ with respect to their tissue distribution, contains structural domains similar to beta chains, differentiation, each formed by a different chain, formerly though to be a beta chain, however, lacks the short alpha region separating domains I and II, migration, neurite outgrowth and metastasis, presumably reflecting diverse functions in vivo, respectively) and they form a cruciform structure consisting of 3 short arms, signaling, Laminin subunit gamma-1 is a protein that in humans is encoded by the LAMC1 gene |
| Immunogen | Amino acids 1566-1579 (KKQEAAIMDYNRDI-human) were used as the immunogen for this Laminin gamma 1 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Laminin gamma 1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Laminin gamma 1 |
| Short name | Laminin gamma 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Laminin g 1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6492 |
| Gene | LAMC1 |
| Long gene name | laminin subunit gamma 1 |
| Synonyms gene | LAMB2 |
| Synonyms gene name | gamma 1 (formerly LAMB2) , laminin |
| Locus | 1q25, 3 |
| Discovery year | 2001-06-22 |
| GenBank acession | J03202 |
| Entrez gene record | 3915 |
| Pubmed identfication | 3234037 |
| RefSeq identity | NM_002293 |
| Classification | Laminin subunits |
| Havana BLAST/BLAT | OTTHUMG00000035418 |