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LAMP-1 Antibody

LAMP-1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLAMP-1 Primary Polyclonal Antibody
Also known asLAMP-1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLAMP-1
SpecificityThis is a highly specific antibody against LAMP-1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range300-350/417
Subcellular location Lysosome, Lumenal
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LAMP-1
Gene ID number3916
Swiss ProtP11279
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI), Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1, This mutant protein then cycles between the plasma membrane and the endosome, Upon cell activation, also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation, Lysosome associated membrane protein (LAMP1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CD17 antigen-like family member A, CD17a, LAMP-1, LAMP1, LGP12, Lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1, LAMPA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLAMP-1
Short nameLAMP-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLAMP-1 (Antibody to)
Alternative techniqueantibodies

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