| Long name | LAT Primary Polyclonal Antibody |
| Also known as | LAT PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | LAT |
| Specificity | This is a highly specific antibody against LAT |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LAT |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen, LAT is expressed in T lymphocytes in interstitial spaces, LAT is not expressed in B cells, epithelial histiocytes and dendritic cells, macrophages, monocytes, plasma cells, platelets and megakaryocytes, which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation, Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 36 kDa phospho tyrosine adapter protein, LAT 1, LAT1, Linker for activation of T cells, Linker for activation of T cells family member 1, p36 38, pp36, Linker for activation of T cell 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | LAT |
| Short name | LAT Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | linker for activation on T cells (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, Cell surfaces, LAT and IDBG-239499 and ENSG00000213658 and 27040, Lat and IDBG-209436 and ENSMUSG00000030742 and 16797, protein kinase binding, this GO :0001772 and immunological synapse and cellular component this GO :0002260 and lymphocyte homeostasis and biological process this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008180 and COP9 signalosome and cellular component this GO :0009967 and positive regulation of signal transduction and biological process this GO :0010467 and gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019722 and calcium-mediated signaling and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042110 and T cell activation and biological process this GO :0042629 and mast cell granule and cellular component this GO :0043303 and mast cell degranulation and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0048872 and homeostasis of number of cells and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050863 and regulation of T cell activation and biological process, this GO :0005070: SH3/SH2 adaptor activity, this GO :0005070: SH3/SH2 adaptor activity and also this GO :0005515: protein binding and also this GO :0019901: protein kinase binding, this GO :0005515: protein binding, this GO :0019901: protein kinase binding, 26847 and IDBG-638875 and ENSBTAG00000021249 and 514735, linker for activation of T cells |
| Identity | 18874 |
| Gene | LAT |
| Long gene name | linker for activation of T-cells |
| Synonyms gene name | linker for activation of T cells |
| Synonyms | LAT1 |
| Synonyms name | linker for activation of T cells, transmembrane adaptor |
| Locus | 16q13 |
| Discovery year | 2002-07-12 |
| GenBank acession | AF036905 |
| Pubmed identfication | 9489702 |
| Havana BLAST/BLAT | OTTHUMG00000131761 |
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