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LAT (Tyr161) Antibody, FITC Conjugated

LAT (Tyr161) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, LAT (Tyr161) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLAT Tyr161
SpecificityThis is a highly specific antibody against LAT Tyr161
ModificationPhosphorylation
Modification siteTyr161
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range145-195/262
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr161
Gene ID number27040
Swiss ProtO43561
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, GRAP2, GRB2, Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, PKC activation, and other signaling molecules, both in mature T-cells and during their development, Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms LAT1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetLAT (Tyr161) Conjugated
Short name FITC Conjugated, LAT (Tyr161) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, linker for activation on T cells (Tyr161) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, Cell surfaces, LAT and IDBG-239499 and ENSG00000213658 and 27040, Lat and IDBG-209436 and ENSMUSG00000030742 and 16797, protein kinase binding, this GO :0001772 and immunological synapse and cellular component this GO :0002260 and lymphocyte homeostasis and biological process this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007265 and Ras protein signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0008180 and COP9 signalosome and cellular component this GO :0009967 and positive regulation of signal transduction and biological process this GO :0010467 and gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019722 and calcium-mediated signaling and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042110 and T cell activation and biological process this GO :0042629 and mast cell granule and cellular component this GO :0043303 and mast cell degranulation and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0048872 and homeostasis of number of cells and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050863 and regulation of T cell activation and biological process, this GO :0005070: SH3/SH2 adaptor activity, this GO :0005070: SH3/SH2 adaptor activity and also this GO :0005515: protein binding and also this GO :0019901: protein kinase binding, this GO :0005515: protein binding, this GO :0019901: protein kinase binding, 26847 and IDBG-638875 and ENSBTAG00000021249 and 514735, linker for activation of T cells
Identity 18874
Gene LAT
Long gene name linker for activation of T-cells
Synonyms gene name linker for activation of T cells
Synonyms name linker for activation of T cells, transmembrane adaptor
Locus 16q13
Discovery year 2002-07-12
GenBank acession AF036905
Pubmed identfication 9489702
Havana BLAST/BLAT OTTHUMG00000131761

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