Name : LAT2 Antibody
Supplier : NJS POLY
Price :389
SKU : GEN4901660391
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | LAT2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Titration of the LAT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This LAT2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9GZY6 |
| Purity | Antigen affinity |
| Description | Binding analysis indicated associations with GRB2, Brdicka et al, By genomic sequence analysis, By immunoprecipitation and immunoblot analysis, Doyle et al, Janssen et al, Member 2, SOS1, They noted that the flanking genes are highly conserved between mouse and human, also known as LAB or NTAL , and, and GAB1 after B-cell receptor activation, indirectly, is a protein that in humans is encoded by the LAT2 gene, with PLCG1 and PLCG2, (2000) mapped the gene to chromosome 7q11, (2002) found that the protein associated with GRB2, (2003) determined that phosphorylation of LAT2 is likely mediated by SYK upon B-cell receptor stimulation, 23, Linker for Activation of T Cells Family |
| Immunogen | Member 2 (KRSEKIYQQRSLRED) was used as the immunogen for this LAT2 antibody, An amino acid sequence from the N-terminus of human Linker for Activation of T Cells Family |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the LAT2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | LAT2 |
| Short name | LAT2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | member 2 (Antibody to), linker to measure activation on T cells family |
| Alternative technique | antibodies |
| Alternative to gene target | BT, LAB and NTAL and WBSCR15 and WBSCR5 and WSCR5, LAT2 and IDBG-21069 and ENSG00000086730 and 7462, Lat2 and IDBG-202957 and ENSMUSG00000040751 and 56743, Plasma membranes, SH2 domain binding, member 2, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019722 and calcium-mediated signaling and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042113 and B cell activation and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042629 and mast cell granule and cellular component this GO :0043303 and mast cell degranulation and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0042169: SH2 domain binding, this GO :0042169: SH2 domain binding, 18889 and IDBG-639943 and ENSBTAG00000045767 and 505016, linker for activation of T cells family |
| Identity | 11066 |
| Gene | SLC7A8 |
| Long gene name | solute carrier family 7 member 8 |
| Synonyms gene name | L system), member 8 , solute carrier family 7 (amino acid transporter light chain |
| Synonyms | LPI-PC1 LAT2 |
| Locus | 14q11, 2 |
| Discovery year | 1999-10-05 |
| GenBank acession | Y18483 |
| Entrez gene record | 23428 |
| Pubmed identfication | 10080183 10391915 |
| Classification | Solute carriers |
| Havana BLAST/BLAT | OTTHUMG00000028720 |