Filters

LATS1 Antibody

LATS1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLATS1 Primary Polyclonal Antibody
Also known asLATS1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLATS1
SpecificityThis is a highly specific antibody against LATS1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LATS1
Gene ID number9113
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Biochemical and genetic data suggest a role as a tumor suppressor, In addition, The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, The protein is phosphorylated in a cell-cycle dependent manner, This is supported by studies in knockout mice showing development of soft-tissue sarcomas, [provided by RefSeq], indicating a role as a negative regulator of CDC2/cyclin A, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments, suggesting potential negative regulation through interference with complex formation via intramolecular binding, the C-terminal kinase domain binds to its own N-terminal region, with late prophase phosphorylation remaining through metaphase, The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names LATS1_HUMAN, Serine threonine protein kinase LATS1, WARTS, WARTS protein kinase, Large tumor suppressor homolog 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLATS1
Short nameLATS1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLATS1 (Antibody to)
Alternative techniqueantibodies
Identity 6514
Gene LATS1
Long gene name large tumor suppressor kinase 1
Synonyms gene name Drosophila) homolog 1 LATS, LATS (large tumor suppressor, homolog 1 (Drosophila) , large tumor suppressor
Synonyms WARTS
Locus 6q25, 1
Discovery year 1999-02-18
GenBank acession AF104413
Entrez gene record 9113
Pubmed identfication 9988268 15122335
RefSeq identity NM_004690
Havana BLAST/BLAT OTTHUMG00000016437

Similar products

Subscribe to our Newsletter