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LATS1 Antibody, ALEXA FLUOR 488

LATS1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, LATS1 Polyclonal Antibody
Also known asAnti-LATS1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLATS1
SpecificityThis is a highly specific antibody against LATS1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LATS1
Gene ID Number9113
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Biochemical and genetic data suggest a role as a tumor suppressor, In addition, The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, The protein is phosphorylated in a cell-cycle dependent manner, This is supported by studies in knockout mice showing development of soft-tissue sarcomas, [provided by RefSeq], indicating a role as a negative regulator of CDC2/cyclin A, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments, suggesting potential negative regulation through interference with complex formation via intramolecular binding, the C-terminal kinase domain binds to its own N-terminal region, with late prophase phosphorylation remaining through metaphase, The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms WARTS
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the LATS1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetLATS1
Short nameLATS1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, LATS1 (Antibody to)
Alternative techniqueantibodies
Identity 6514
Gene LATS1
Long gene name large tumor suppressor kinase 1
Synonyms gene name Drosophila) homolog 1 LATS, LATS (large tumor suppressor, homolog 1 (Drosophila) , large tumor suppressor
Locus 6q25, 1
Discovery year 1999-02-18
GenBank acession AF104413
Entrez gene record 9113
Pubmed identfication 9988268 15122335
RefSeq identity NM_004690
Havana BLAST/BLAT OTTHUMG00000016437

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