Name : LATS1 Antibody, Cy5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN1614737663
| Long name | Cy5 Conjugated, LATS1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | LATS1 |
| Specificity | This is a highly specific antibody against LATS1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human LATS1 |
| Gene ID number | 9113 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Biochemical and genetic data suggest a role as a tumor suppressor, In addition, The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, The protein is phosphorylated in a cell-cycle dependent manner, This is supported by studies in knockout mice showing development of soft-tissue sarcomas, [provided by RefSeq], indicating a role as a negative regulator of CDC2/cyclin A, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments, suggesting potential negative regulation through interference with complex formation via intramolecular binding, the C-terminal kinase domain binds to its own N-terminal region, with late prophase phosphorylation remaining through metaphase, The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Synonyms | WARTS |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | LATS1 Conjugated |
| Short name | Conjugated, LATS1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Alternative name | cyanine 5 coupled, LATS1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6514 |
| Gene | LATS1 |
| Long gene name | large tumor suppressor kinase 1 |
| Synonyms gene name | Drosophila) homolog 1 LATS, LATS (large tumor suppressor, homolog 1 (Drosophila) , large tumor suppressor |
| Locus | 6q25, 1 |
| Discovery year | 1999-02-18 |
| GenBank acession | AF104413 |
| Entrez gene record | 9113 |
| Pubmed identfication | 9988268 15122335 |
| RefSeq identity | NM_004690 |
| Havana BLAST/BLAT | OTTHUMG00000016437 |