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LATS1 Antibody, Cy7 Conjugated

LATS1 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, LATS1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLATS1
SpecificityThis is a highly specific antibody against LATS1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human LATS1
Gene ID number9113
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Biochemical and genetic data suggest a role as a tumor suppressor, In addition, The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, The protein is phosphorylated in a cell-cycle dependent manner, This is supported by studies in knockout mice showing development of soft-tissue sarcomas, [provided by RefSeq], indicating a role as a negative regulator of CDC2/cyclin A, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments, suggesting potential negative regulation through interference with complex formation via intramolecular binding, the C-terminal kinase domain binds to its own N-terminal region, with late prophase phosphorylation remaining through metaphase, The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms WARTS
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetLATS1 Conjugated
Short name Conjugated, LATS1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, LATS1 (Antibody to)
Alternative techniqueantibodies
Identity 6514
Gene LATS1
Long gene name large tumor suppressor kinase 1
Synonyms gene name Drosophila) homolog 1 LATS, LATS (large tumor suppressor, homolog 1 (Drosophila) , large tumor suppressor
Locus 6q25, 1
Discovery year 1999-02-18
GenBank acession AF104413
Entrez gene record 9113
Pubmed identfication 9988268 15122335
RefSeq identity NM_004690
Havana BLAST/BLAT OTTHUMG00000016437

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