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LC3 Antibody

LC3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLC3 Primary Polyclonal Antibody
Also known asLC3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLC3
SpecificityThis is a highly specific antibody against LC3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range27-59/121
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LC3
Gene ID number 81631, 84557
Swiss Prot Q9GZQ8, Q9H492
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway, Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation, Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 1, MAP1 light chain 3-like protein 2, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 A, MAP1A/MAP1B light chain 3 B, Microtubule-associated protein 1 light chain 3 alpha Microtubule-associated proteins 1A/1B light chain 3B LC3B: Autophagy-related protein LC3 B, Microtubule-associated protein 1 light chain 3 beta, LC3A: Microtubule-associated proteins 1A/1B light chain 3A
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLC3
Short nameLC3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLC3 (Antibody to)
Alternative techniqueantibodies
Identity 6838
Gene MAP1LC3A
Long gene name microtubule associated protein 1 light chain 3 alpha
Synonyms MAP1BLC3 MAP1ALC3 LC3 LC3A ATG8E
Locus 20q11, 22
Discovery year 2000-06-29
Entrez gene record 84557
Pubmed identfication 8833088 17580304
RefSeq identity NM_181509
Classification Autophagy related
Havana BLAST/BLAT OTTHUMG00000032306

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