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LC3 Antibody, ALEXA FLUOR 488

LC3 Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, LC3 Polyclonal Antibody
Also known asAnti-LC3 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLC3
SpecificityThis is a highly specific antibody against LC3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range27-59/121
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LC3
Gene ID Number 81631, 84557
Swiss Prot Q9GZQ8, Q9H492
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway, Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation, Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms MAP1BLC3 MAP1ALC3 LC3 LC3A ATG8E
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the LC3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetLC3
Short nameLC3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, LC3 (Antibody to)
Alternative techniqueantibodies
Identity 6838
Gene MAP1LC3A
Long gene name microtubule associated protein 1 light chain 3 alpha
Locus 20q11, 22
Discovery year 2000-06-29
Entrez gene record 84557
Pubmed identfication 8833088 17580304
RefSeq identity NM_181509
Classification Autophagy related
Havana BLAST/BLAT OTTHUMG00000032306

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