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Lefty Antibody, Cy5.5 Conjugated

Lefty Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, Lefty Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLefty
SpecificityThis is a highly specific antibody against Lefty
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Lefty
Gene ID number10637
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Cleavage is therefore an essential step for Lefty activation, Complexes formed move into the nucleus, Lefty, Lefty acts to inhibit phosphorylation of Smad2 following activation of the TGF beta receptor, Lefty also inhibits events downstream from R Smad phosphorylation, Lefty is synthesized as a large inactive precursor (41 Kda) that must be endoproteolytically processed to release the bioactive polypeptide (28 kDa and 34 kDa forms), Lefty provides a repressed state of TGF beta responsive genes, Members of the TGF beta superfamily require processing for their activation, Secreted growth factors of the TGF beta family, TGF beta (Transforming growth factor beta) is a pleiotropic cytokine that regulates growth and differentiation of diverse types of cells, TGF beta actions are directed by ligand induced activation of TGF beta receptors, The 28kDa form induces MAPK activity, The Lefty family is comprised of Lefty 1 and Lefty 2 in mouse, a left right axis is established, a novel member of the TGF beta superfamily, and Lefty A and Lefty B in humans, including gene products derived from nodal, inhibits TGF beta signaling, lefty 1 and lefty 2, play crucial roles in establishing left right asymmetries, where they act as components of a transcriptional complex, During vertebrate embryogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms AI450052, Ebaf, FACTOR B, HOMOLOG OF antibody, LEFT-RIGHT DETERMINATION, LEFT-RIGHT DETERMINATION FACTOR 1, LEFTB, LEFTY 1, LEFTY B, LEFTY1, LEFTY1, LEFTY1, LEFTYB, Left right determination factor 1, Left right determination factor B, Lefty, MOUSE, Protein lefty-B, RGD1561867, STRA3, Stimulated by retinoic acid gene 3 protein, TGF beta 4, TGF-beta-4, Tgfb4, Transforming growth factor beta 4, Transforming growth factor beta-4, factor B, left right determination factor, left-right determination, left-right determination factor, lefty-1, Protein lefty-1
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetLefty Conjugated
Short name Conjugated, Lefty Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, Lefty (Antibody to)
Alternative techniqueantibodies

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