Filters

Leptin Receptor Antibody (LEPR)

Leptin Receptor Antibody (LEPR) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenLeptin Receptor (LEPR)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the Leptin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Leptin Receptor antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P48357
PurityAntigen affinity
Description Alternatively spliced transcript variants encoding different isoforms have been described for this gene, It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, Mutations in this gene have been associated with obesity and pituitary dysfunction, This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis, encode distinct proteins (PMID:9207021), however, The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins
ImmunogenA portion of amino acids 957-986 from the human protein was used as the immunogen for this Leptin Receptor antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Leptin Receptor antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene LEPR
Gene targetLeptin Receptor (LEPR)
Short nameLeptin Receptor Antibody (LEPR)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLeptin Receptor (Antibody to) (leptin receptor)
Alternative techniqueantibodies
Alternative to gene target CD295 and LEP-R and LEPRD and OB-R and OBR, Extracellular, LEPR and IDBG-638266 and ENSBTAG00000005910 and 497205, LEPR and IDBG-99469 and ENSG00000116678 and 3953, Lepr and IDBG-167734 and ENSMUSG00000057722 and 16847, identical protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004896 and cytokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006112 and energy reserve metabolic process and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043235 and receptor complex and cellular component this GO :0045721 and negative regulation of gluconeogenesis and biological process this GO :0051346 and negative regulation of hydrolase activity and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0004896: cytokine receptor activity and also this GO :0005515: protein binding and also this GO :0042802: identical protein binding, this GO :0004896: cytokine receptor activity, this GO :0005515: protein binding, this GO :0042802: identical protein binding, 785813, leptin receptor
Identity 6554
Long gene name leptin receptor
Synonyms OBR CD295
Locus 1p31, 3
Discovery year 1996-05-09
GenBank acession U43168
Entrez gene record 3953
Pubmed identfication 8548812 8812446
RefSeq identity NM_002303
Classification CD molecules Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000009115
Locus Specific Databases LRG_283

Similar products

Subscribe to our Newsletter