Name : LGI4 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6156584200
| Long name | LGI4 Primary Polyclonal Antibody |
| Also known as | LGI4 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | LGI4 |
| Specificity | This is a highly specific antibody against LGI4 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LGI4 |
| Gene ID number | 163175 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ER and vesicles, Interestingly, LGI1, LGI2 and LGI3, LGI4 is localized subcellularly to the Golgi, LGI4 shares significant homology with its other family members, Significantly, There are two isoforms of LGI4 that are produced as a result of alternative splicing events, also known as leucine-rich glioma-inactivated protein 4, given the sequence similarity of LGI4, is a 537 amino acid secreted glycosylated protein that is widely expressed, it is likely that it also may be implicated in the pathology of seizures, mutations in the gene encoding LGI1 have been linked to human temporal lobe epilepsy and, siRNA knockdown studies of LGI4 expression in Schwann cells have been shown to result in the inhibition of myelination, thus suggesting that LGI4 is an essential component of myelin formation and axon segregation, with highest levels found within the nervous system, LGI4 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | LGI1 like protein 3, LGI4, LGI4_HUMAN, Leucine rich glioma inactivated protein 4, Leucine rich repeat LGI family member 4, Lgi4 protein, Lgil3, leucine-rich repeat LGI family member 4, Leucine rich glioma inactivated gene 4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | LGI4 |
| Short name | LGI4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | LGI4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 18712 |
| Gene | LGI4 |
| Long gene name | leucine rich repeat LGI family member 4 |
| Synonyms gene name | leucine-rich repeat LGI family, member 4 |
| Locus | 19q13, 12 |
| Discovery year | 2002-05-30 |
| GenBank acession | AJ487519 |
| Entrez gene record | 163175 |
| Pubmed identfication | 12023020 |
| Havana BLAST/BLAT | OTTHUMG00000044558 |