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LGI4 Antibody, FITC Conjugated

LGI4 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, LGI4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLGI4
SpecificityThis is a highly specific antibody against LGI4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human LGI4
Gene ID number163175
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ER and vesicles, Interestingly, LGI1, LGI2 and LGI3, LGI4 is localized subcellularly to the Golgi, LGI4 shares significant homology with its other family members, Significantly, There are two isoforms of LGI4 that are produced as a result of alternative splicing events, also known as leucine-rich glioma-inactivated protein 4, given the sequence similarity of LGI4, is a 537 amino acid secreted glycosylated protein that is widely expressed, it is likely that it also may be implicated in the pathology of seizures, mutations in the gene encoding LGI1 have been linked to human temporal lobe epilepsy and, siRNA knockdown studies of LGI4 expression in Schwann cells have been shown to result in the inhibition of myelination, thus suggesting that LGI4 is an essential component of myelin formation and axon segregation, with highest levels found within the nervous system, LGI4
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetLGI4 Conjugated
Short name FITC Conjugated, LGI4 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, LGI4 (Antibody to)
Alternative techniqueantibodies
Identity 18712
Gene LGI4
Long gene name leucine rich repeat LGI family member 4
Synonyms gene name leucine-rich repeat LGI family, member 4
Locus 19q13, 12
Discovery year 2002-05-30
GenBank acession AJ487519
Entrez gene record 163175
Pubmed identfication 12023020
Havana BLAST/BLAT OTTHUMG00000044558

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