| Long name | LIF Primary Polyclonal Antibody |
| Also known as | LIF PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | LIF |
| Specificity | This is a highly specific antibody against LIF |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 177-202/202 |
| Subcellular location | Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LIF |
| Gene ID number | 3976 |
| Swiss Prot | P15018 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, and the stimulation of acute-phase protein synthesis in hepatocytes, the induction of neuronal cell differentiation, LIF has the capacity to induce terminal differentiation in leukemic cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | D factor, DIA, Differentiation-stimulating factor, HILDA, LIF, Leukemia inhibitory factor, MLPLI, Melanoma-derived LPL inhibitor, CDF |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | LIF |
| Short name | LIF Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | leukemia inhibitory factor (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CDF and DIA and HILDA and MLPLI, Extracellular, LIF and IDBG-3968 and ENSG00000128342 and 3976, LIF and IDBG-636335 and ENSBTAG00000007424 and 280840, Lif and IDBG-142317 and ENSMUSG00000034394 and 16878, growth factor activity, this GO :0001135 and RNA polymerase II transcription factor recruiting transcription factor activity and molecular function this GO :0001974 and blood vessel remodeling and biological process this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005146 and leukemia inhibitory factor receptor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006955 and immune response and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007566 and embryo implantation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0030324 and lung development and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0033141 and positive regulation of peptidyl-serine phosphorylation of STAT protein and biological process this GO :0042503 and tyrosine phosphorylation of Stat3 protein and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0045651 and positive regulation of macrophage differentiation and biological process this GO :0045835 and negative regulation of meiosis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046697 and decidualization and biological process this GO :0046888 and negative regulation of hormone secretion and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048644 and muscle organ morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048711 and positive regulation of astrocyte differentiation and biological process this GO :0048861 and leukemia inhibitory factor signaling pathway and biological process this GO :0048863 and stem cell differentiation and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0060426 and lung vasculature development and biological process this GO :0060463 and lung lobe morphogenesis and biological process this GO :0060707 and trophoblast giant cell differentiation and biological process this GO :0060708 and spongiotrophoblast differentiation and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0072108 and positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0072307 and regulation of metanephric nephron tubule epithelial cell differentiation and biological process this GO :1900182 and positive regulation of protein localization to nucleus and biological process this GO :1901676 and positive regulation of histone H3-K27 acetylation and biological process, this GO :0001135: RNA polymerase II transcription factor recruiting transcription factor activity, this GO :0001135: RNA polymerase II transcription factor recruiting transcription factor activity and also this GO :0005102: receptor binding and also this GO :0005125: cytokine activity and also this GO :0005146: leukemia inhibitory factor receptor binding and also this GO :0008083: growth factor activity, this GO :0005102: receptor binding, this GO :0005125: cytokine activity, this GO :0005146: leukemia inhibitory factor receptor binding, this GO :0008083: growth factor activity, leukemia inhibitory factor |
| Identity | 6596 |
| Gene | LIF |
| Long gene name | leukemia inhibitory factor |
| Synonyms | CDF DIA HILDA |
| Synonyms name | differentiation inhibitory activity differentiation-inducing factor hepatocyte-stimulating factor III cholinergic differentiation factor human interleukin in DA cells |
| Locus | 22q12, 2 |
| Discovery year | 1989-06-11 |
| Entrez gene record | 3976 |
| Pubmed identfication | 1714745 8058719 |
| RefSeq identity | NM_002309 |
| Classification | Endogenous ligands Interleukin 6 cytokine family |
| Havana BLAST/BLAT | OTTHUMG00000150910 |
| Locus Specific Databases | ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |
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