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LIM kinase 1 + 2 Antibody

LIM kinase 1 + 2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLIM kinase 1 + 2 Primary Polyclonal Antibody
Also known asLIM kinase 1 + 2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLIM kinase 1 + 2
SpecificityThis is a highly specific antibody against LIM kinase 1 + 2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LIM kinase 1 + 2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen LIMK1 is highly active in the brain and spinal chord, LIMK1 is specifically stimulated by Rac, LIMK1 may play an important role in areas of the brain that are responsible for processing visual-spatial information (visuospatial constructive cognition), Rho and Cdc42, These parts of the brain are important for visualizing an object as a set of parts and performing tasks such as writing, They can phosphorylate an actin-binding protein, and assembling puzzles, cofilin which binds to actin monomers and polymers and promotes the disassembly of actin filament, constructing models, drawing, one of the Rho family proteins, suggesting that two distinct pathways exist in the Rho family driven actin cytoskeleton dynamics, through control of the organization of actin filaments, where it is believed to be involved in the development of nerve cells whilst LIMK2 is ubiquitously expressed in many adult tissues, while LIMK2 activity is activated under the control of other Rho family members, LIMK 1 and 2 likely regulate aspects of the cytoskeleton, The phosphorylation of cofilin via LIMK inactivates this potential
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names LIM domain kinase 1, LIM domain kinase 2, LIMK1, LIMK1+LIMK2, LIMK2, LIMK2_HUMAN, LIM kinase 1+2, LIMK1_HUMAN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLIM kinase 1 + 2
Short nameLIM kinase 1 + 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLIM phosphorylation catalyst 1 and 2 (Antibody to)
Alternative techniqueantibodies
Identity 17468
Gene PDLIM5
Long gene name PDZ and LIM domain 5
Synonyms LIM Enh
Locus 4q22, 3
Discovery year 2005-01-12
GenBank acession AF061258
Entrez gene record 10611
Pubmed identfication 15346770
Classification LIM domain containing PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000130973

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