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LIM kinase 1 + 2 Antibody, HRP Conjugated

LIM kinase 1 + 2 Antibody, HRP Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name HRP Conjugated, LIM kinase 1 + 2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationHRP Conjugated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLIM kinase 1 + 2
SpecificityThis is a highly specific antibody against LIM kinase 1 + 2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human LIM kinase 1 + 2
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background LIMK1 is highly active in the brain and spinal chord, LIMK1 is specifically stimulated by Rac, LIMK1 may play an important role in areas of the brain that are responsible for processing visual-spatial information (visuospatial constructive cognition), Rho and Cdc42, These parts of the brain are important for visualizing an object as a set of parts and performing tasks such as writing, They can phosphorylate an actin-binding protein, and assembling puzzles, cofilin which binds to actin monomers and polymers and promotes the disassembly of actin filament, constructing models, drawing, one of the Rho family proteins, suggesting that two distinct pathways exist in the Rho family driven actin cytoskeleton dynamics, through control of the organization of actin filaments, where it is believed to be involved in the development of nerve cells whilst LIMK2 is ubiquitously expressed in many adult tissues, while LIMK2 activity is activated under the control of other Rho family members, LIMK 1 and 2 likely regulate aspects of the cytoskeleton, The phosphorylation of cofilin via LIMK inactivates this potential
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms LIM Enh
Properties Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase 
Gene targetLIM kinase 1 + 2 Conjugated
Short name Conjugated, LIM kinase 1 + 2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelHRP
Alternative name horseradish peroxidase coupled, LIM phosphorylation catalyst 1 and 2 (Antibody to)
Alternative techniqueantibodies
Identity 17468
Gene PDLIM5
Long gene name PDZ and LIM domain 5
Locus 4q22, 3
Discovery year 2005-01-12
GenBank acession AF061258
Entrez gene record 10611
Pubmed identfication 15346770
Classification LIM domain containing PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000130973

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