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Lin-28 Antibody

Lin-28 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameLin-28 Primary Polyclonal Antibody
Also known asLin-28 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLin-28
SpecificityThis is a highly specific antibody against Lin-28
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range70-120/250
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lin-28B
Gene ID number 79727, 389421
Swiss ProtQ6ZN17, Q9H9Z2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, Isoform 1, Isoform 2 has no effect on cell growth, Mediates MYC-mediated let-7 repression, Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7, Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation, a miRNA precursor, leading to the terminal uridylation of pre-let-7, leading to their terminal uridylation and subsequent degradation, stimulates growth of the breast adenocarcinoma cell line MCF-7, when overexpressed, Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CSDD 2, CSDD2, FLJ16517, LIN28B, LN28B_HUMAN, Lin 28, Lin 28 homolog B C, Lin-28A, Lin-28B, Protein lin-28 homolog A, Protein lin-28 homolog B, Zinc finger CCHC domain-containing protein 1, elegans, 2, Lin28B
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetLin-28
Short nameLin-28 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLin-28 (Antibody to)
Alternative techniqueantibodies
Identity 15986
Gene LIN28A
Long gene name lin-28 homolog A
Synonyms gene LIN28
Synonyms gene name elegans) , lin-28 homolog (C
Synonyms LIN-28 FLJ12457 ZCCHC1 CSDD1
Locus 1p36, 11
Discovery year 2003-07-21
GenBank acession AF521099
Entrez gene record 79727
Pubmed identfication 12798299
RefSeq identity NM_024674
Classification Zinc fingers CCHC-type
Havana BLAST/BLAT OTTHUMG00000003550

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