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Lin-28 Antibody, ALEXA FLUOR 350

Lin-28 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, Lin-28 Polyclonal Antibody
Also known asAnti-Lin-28 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLin-28
SpecificityThis is a highly specific antibody against Lin-28
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range70-120/250
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Lin-28B
Gene ID Number 79727, 389421
Swiss ProtQ6ZN17, Q9H9Z2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, Isoform 1, Isoform 2 has no effect on cell growth, Mediates MYC-mediated let-7 repression, Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7, Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation, a miRNA precursor, leading to the terminal uridylation of pre-let-7, leading to their terminal uridylation and subsequent degradation, stimulates growth of the breast adenocarcinoma cell line MCF-7, when overexpressed, Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms LIN-28 FLJ12457 ZCCHC1 CSDD1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetLin-28
Short nameLin-28 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Lin-28 (Antibody to)
Alternative techniqueantibodies
Identity 15986
Gene LIN28A
Long gene name lin-28 homolog A
Synonyms gene LIN28
Synonyms gene name elegans) , lin-28 homolog (C
Locus 1p36, 11
Discovery year 2003-07-21
GenBank acession AF521099
Entrez gene record 79727
Pubmed identfication 12798299
RefSeq identity NM_024674
Classification Zinc fingers CCHC-type
Havana BLAST/BLAT OTTHUMG00000003550

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