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Lin-28 Antibody, Cy7 Conjugated

Lin-28 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, Lin-28 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenLin-28
SpecificityThis is a highly specific antibody against Lin-28
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range70-120/250
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human Lin-28B
Gene ID number 79727, 389421
Swiss ProtQ6ZN17, Q9H9Z2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, Isoform 1, Isoform 2 has no effect on cell growth, Mediates MYC-mediated let-7 repression, Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7, Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation, a miRNA precursor, leading to the terminal uridylation of pre-let-7, leading to their terminal uridylation and subsequent degradation, stimulates growth of the breast adenocarcinoma cell line MCF-7, when overexpressed, Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms CSDD 2, CSDD2, FLJ16517, LIN28B, LN28B_HUMAN, Lin 28, Lin 28 homolog B C, Lin-28A, Lin-28B, Protein lin-28 homolog A, Protein lin-28 homolog B, Zinc finger CCHC domain-containing protein 1, elegans, 2, Lin28B
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetLin-28 Conjugated
Short name Conjugated, Lin-28 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, Lin-28 (Antibody to)
Alternative techniqueantibodies

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