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LIN28A (55CT58.12.1) Monoclonal Antibody

LIN28A (55CT58.12.1) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name1) Monoclonal Antibody, 12, LIN28A (55CT58
Also known as1) Monoclonal Antibody, 12, LIN28A (55CT58
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenLIN28A
SpecificityThis is a highly specific antibody against LIN28A
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1, 12, 55CT58
SourceLIN28A recombinant protein is used to produce this monoclonal antibody
Gene ID number79727
Swiss ProtQ9H9Z2
Tested Applications IF, IHC-P, WB
Recommended dilutions IF(1:10~50), IHC-P(1:50~200), WB(1:200~2000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ARBP/36B4 ribosomal protein mRNA and its own mRNA, Binds IGF2 mRNA, Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity), Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, MYOD1 mRNA, Specifically binds miRNA precursors (pre-miRNAs), Suppressor of microRNA (miRNA) biogenesis, The repression of let-7 expression is required for normal development and contributes to maintain the pluripotent state by preventing let-7-mediated differentiation of embryonic stem cells (By similarity), This results in the terminal uridylation of target pre-miRNAs (PubMed:19703396) (PubMed:22118463) (PubMed:22898984), Uridylated pre-miRNAs fail to be processed by Dicer and undergo degradation, and recruits ZCCHC11/TUT4 uridylyltransferase, in mRNA stabilization, including that of let-7, indirectly, miR-143 and miR-200c, miR107, recognizing an 5'-GGAG-3' motif found in pre-miRNA terminal loop, Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis
Purification method This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names LIN-28, LIN28, LIN28A, Protein lin-28 homolog A, ZCCHC1, Zinc finger CCHC domain-containing protein 1, lin-28A, CSDD1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target1) Monoclonal, 12, LIN28A (55CT58
Short name1) Monoclonal Antibody, 12, LIN28A (55CT58
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name1) monoclonal (Antibody to), 12, LIN28A (55CT58
Alternative techniqueantibodies
Identity 15986
Gene LIN28A
Long gene name lin-28 homolog A
Synonyms gene LIN28
Synonyms gene name elegans) , lin-28 homolog (C
Synonyms LIN-28 FLJ12457 ZCCHC1 CSDD1
Locus 1p36, 11
Discovery year 2003-07-21
GenBank acession AF521099
Entrez gene record 79727
Pubmed identfication 12798299
RefSeq identity NM_024674
Classification Zinc fingers CCHC-type
Havana BLAST/BLAT OTTHUMG00000003550

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